Mucina salival en pacientes obesos en relación al tratamiento de la enfermedad periodontal
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Graphimedic S.A.
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La mucina salival (Ms) modula otras proteínas salivales
que participan en múltiples funciones fisiológicas de la cavidad oral.
Los niveles de Ms pueden proporcionar información sobre el estado
de inflamación de los tejidos periodontales. Por tanto, el objetivo del
presente estudio fue evaluar los niveles Ms en pacientes obesos y no
obesos, antes y después del tratamiento periodontal. Material y mé todos: Un total de 60 pacientes fueron distribuidos en seis grupos, de
acuerdo al índice de masa corporal (IMC) y la gravedad de la enferme dad periodontal (EP). Valores del IMC superiores a 27 correspondían a
obesidad. La EP en el momento del diagnóstico se designó como leve,
moderada o severa. Se recolectaron muestras de saliva completa, antes
(MU-A) y después (MU-D) del tratamiento periodontal. Se evaluaron
los niveles de Ms utilizando el método de Azul Alcian. Los resultados
se analizaron con el Software InfoStat, mediante estadística descriptiva
e inferencial. Resultados: Los valores de MU-A fueron superiores a los
contenidos de MU-D (p < 0.0001). Las variaciones entre los pacientes
no obesos y obesos fueron mínimas. A medida que aumentó el nivel
de la EP, las variables MU-A y MU-D mostraron una disminución
progresiva (p = 0.0032). Conclusiones: El nivel de Ms fue mayor en
la saliva de los pacientes con EP no tratada. Ms se puede utilizar como
marcador inflamatorio para la detección de EP.
Salivary mucin (sM) modulates other salivary proteins that participate in multiple physiological functions of the oral cavity. sM levels can provide information on the state of inflammation of the periodontium. Therefore, the objective of the present study was to evaluate sM levels in obese and non-obese patients, before and after periodontal treatment. Material and methods: A total of 60 patients were distributed into six groups, according to the body mass index (BMI) and the severity of the periodontal disease (PD). BMI values higher than 27 corresponded to obesity. PD at the time of diagnosis was designated as mild, moderate, or severe. Complete saliva samples were collected before (MU-B) and after (MU-A) the periodontal treatment. sM levels were evaluated using the Alcian Blue method. The results were analyzed with the InfoStat Software, using descriptive and inferential statistics. Results: MU-B values were higher than MU-A contents (p < 0.0001). Variations between non-obese and obese patients were minimal. As the level of PD increased, the variables MU-A and MU-D showed a progressive decrease (p = 0.0032). Conclusions: The level of sM was higher in the saliva of patients with untreated PD. sM can be used as an inflammatory marker for the detection of PD.
Salivary mucin (sM) modulates other salivary proteins that participate in multiple physiological functions of the oral cavity. sM levels can provide information on the state of inflammation of the periodontium. Therefore, the objective of the present study was to evaluate sM levels in obese and non-obese patients, before and after periodontal treatment. Material and methods: A total of 60 patients were distributed into six groups, according to the body mass index (BMI) and the severity of the periodontal disease (PD). BMI values higher than 27 corresponded to obesity. PD at the time of diagnosis was designated as mild, moderate, or severe. Complete saliva samples were collected before (MU-B) and after (MU-A) the periodontal treatment. sM levels were evaluated using the Alcian Blue method. The results were analyzed with the InfoStat Software, using descriptive and inferential statistics. Results: MU-B values were higher than MU-A contents (p < 0.0001). Variations between non-obese and obese patients were minimal. As the level of PD increased, the variables MU-A and MU-D showed a progressive decrease (p = 0.0032). Conclusions: The level of sM was higher in the saliva of patients with untreated PD. sM can be used as an inflammatory marker for the detection of PD.
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Celia, Armando César, et al., 2021. Mucina salival en pacientes obesos en relación al tratamiento de la enfermedad periodontal. Revista ADM. México, D. F.: Graphimedic S.A, vol. 78, no. 5, p. 264-269. ISSN 0001-0944.
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