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Tumor biology of non-metastatic stages of clear cell renal cell carcinoma; overexpression of stearoyl desaturase-1, EPO/EPO-R system and hypoxia-related proteins
(Springer, 2016-07-28)
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal carcinoma. There is great interest to know the molecular basis of the tumor biology of ccRCC that might contribute to a better understanding of ...
Amelioration of lipopolysaccharide-induced acute kidney injury by erythropoietin : involvement of mitochondria-regulated apoptosis
(Elsevier Ireland Ltd, 2014)
Sepsis remains the most important cause of acute kidney injury (AKI) in critically ill patients and is an independent predictor of poor outcome. The administration of lipopolysaccharide (LPS) to animals reproduces most of ...
Molecular mechanisms involved in murine bone marrow erythropoietic response to acute anaemia by bleeding
(Science Alert, 2013)
The underlying interactions among apoptosis, eiythroid proliferation and differentiation involved in bone marrow eiythropoietic response after an acute blood-loss have not yet been elucidated in detail. We hypothesized ...
Erythropoietin attenuates renal and pulmonary injury in polymicrobial induced-sepsis through EPO-R, VEGF and VEGF-R2 modulation
(Elsevier, 2016)
Sepsis remains the most important cause of acute kidney injury (AKI) and acute lung injury (ALI) in critically ill patients. The cecal ligation and puncture (CLP) model in experimental mice reproduces most of the clinical ...
Expresión diferencial de isoformas del factor inducible por hipoxia (hif-1α y hif-2 α) en bazo y médula ósea en un modelo murino
(Universidad Nacional del Nordeste. Facultad de Medicina, 2016-10-08)
Los factores inducibles por hipoxia (HIFs) regulan la adaptación a la hipoxia (H) y protegen a las células induciendo la transcripción de múltiples genes. Se propone estudiar la expresión de las isoformas HIF1α y HIF2α en ...